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Gastrointestinal perforation

Definition
Treatment
Alternative Names
Expectations (prognosis)
Causes, incidence, and risk factors
Complications
Symptoms
Calling your health care provider
Signs and tests
Prevention


Digestive system
Digestive system
Digestive system organs
Digestive system organs

 Definition  

Gastrointestinal perforation is a hole that passes through the entire wall of the stomach, small intestine or large bowel. This condition is a medical emergency.

 Alternative Names  

Intestinal perforation; Perforation of the intestines

 Causes, incidence, and risk factors  

Gastrointestinal perforation can be caused by a variety of illnesses, including appendicitis, diverticulitis, ulcer disease, Crohn's disease, and less commonly, infections of the bowel, such as infectious colitis.

Perforation of the intestine leads to leakage of intestinal contents into the abdominal cavity. This causes an inflammation called peritonitis.

 Symptoms  

Symptoms may include:

  • Severe abdominal pain
  • Fever
  • Nausea
  • Vomiting

 Signs and tests  

X-rays of the abdomen may show air in the abdominal cavity, suggesting a perforation. CT scan of the abdomen often shows the location of the perforation. The person's white blood cell (WBC) count is often higher than normal.

 Treatment  

Treatment usually involves surgery to repair the hole (perforation). Occasionally, a small part of the intestine must be removed. A temporary colostomy or ileostomy may be needed.

In rare cases, antibiotics alone can be used to treat patients whose perforations have closed. This can be confirmed by a physical exam, blood tests, and x-rays.

 Expectations (prognosis)  

Surgery is usually successful, but depends on the severity of the perforation and the length of time to treatment.

 Complications  

Complications include bleeding, infection, and formation of intra-abdominal abscesses.

 Calling your health care provider  

Call your doctor if you have severe abdominal pain, fever, nausea, vomiting, or severe changes in bowel habits.

 Prevention  

Depending on the cause, perforation can be prevented by preventing any underlying disease that may lead to intestinal perforation. Ulcer disease should be treated with appropriate medicines. Patients with diverticulitis must follow a high fiber diet.

Review date: 7/14/2006

Reviewed By: J.A. Lee, M.D., Division of Surgery, UCSF, San Francisco, CA. Review provided by VeriMed Healthcare Network.

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