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Gastritis - chronic

Definition
Expectations (prognosis)
Alternative Names
Complications
Causes, incidence, and risk factors
Calling your health care provider
Symptoms
Prevention
Signs and tests
References
Treatment


Digestive system
Digestive system
Digestive system organs
Digestive system organs

 Definition  

Chronic gastritis is an inflammation of the lining of the stomach that occurs gradually and persists for a prolonged time.

 Alternative Names  

Chronic gastritis

 Causes, incidence, and risk factors  

Chronic gastritis may be caused by prolonged irritation from the use of nonsteroidal anti-inflammatory drugs (NSAIDs), infection with the bacteria Helicobacter pylori, pernicious anemia (an autoimmune disorder), degeneration of the lining of the stomach from age, or chronic bile reflux.

Many people with chronic gastritis have no symptoms of the condition.

 Symptoms  

  • Upper abdominal pain, possibly aggravated by eating
  • Abdominal indigestion
  • Loss of appetite
  • Nausea
  • Vomiting
  • Vomiting blood or coffee-ground like material
  • Dark stools
Note: there may be no symptoms

 Signs and tests  

  • EGD (esophagogastroduodenoscopy) and biopsy showing gastritis
  • CBC showing anemia
  • A guaiac stool test

 Treatment  

The treatment depends on the cause of the gastritis. Antibiotic therapy will treat chronic gastritis caused by infection with Helicobacter pylori.

Antacids or other medications, such as cimetidine (to decrease or neutralize gastric acid in the stomach) or proton pump inhibitors such as Prilosec, will usually eliminate the symptoms and promote healing. Medications known to cause gastritis should be discontinued. Gastritis caused by pernicious anemia is treated with vitamin B12.

 Expectations (prognosis)  

Most gastritis improves rapidly with treatment. Prognosis depends on the underlying cause. Most chronic gastritis does not cause symptoms and does not result in significant illness.

 Complications  

Loss of blood and increased risk of gastric cancer are potential complications.

 Calling your health care provider  

Call your health care provider if symptoms of gastritis do not improve with treatment. Call your health care provider if you are vomiting blood or producing bloody stools.

 Prevention  

Avoid use of aspirin or NSAIDs if you are prone to gastritis.

 References  

Howden CW, Hunt RH. Guidelines for the management of Helicobacter pylori infection. Ad Hoc Committee on Practice Parameters of the American College of Gastroenterology. Am J Gastroenterol. 1998 Dec;93(12):2330-8.

Review date: 5/3/2007

Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

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